When Brian Reale first founded ProcessMaker in 2000, it ran out of money within a year and then went into a corporate coma for five more. But he persisted, and the now-Durham-based company currently has 130 employees—16 of them in the U.S. and the rest international—and are approaching $10M in annual revenue without ever taking outside investment. What do they do, you ask? We’ll let the Duke grad tell you that, and much more.